Orthopaedic Surgeon Questions Orthopaedic Surgeon

Osteoporosis questions?

1. Who should have a bone density test?

2. How is a diagnosis of osteoporosis established?

3. How should patients who have low bone mineral density be evaluated?

4. How should patients be monitored for response to therapy?


3 Answers

A bone density test, also known as a dual-energy X-ray absorptiometry (DXA) scan, is recommended for certain individuals to assess their risk of osteoporosis. The following groups of people should consider having a bone density test:
Women aged 65 and older
Men aged 70 and older
Postmenopausal women under the age of 65 with risk factors for osteoporosis (e.g., family history, low body weight, smoking, certain medical conditions)
Men aged 50-69 with risk factors for osteoporosis
Individuals with a fracture or significant height loss
Individuals on certain medications known to contribute to bone loss (e.g., long-term corticosteroid use)

A diagnosis of osteoporosis is usually established through a combination of medical history, physical examination, review of risk factors, and bone density testing. To diagnose osteoporosis, a bone density test is conducted, and the results are compared to a reference standard called a T-score. A T-score of -2.5 or lower is indicative of osteoporosis. Additionally, the presence of a fragility fracture (a fracture resulting from minimal trauma) is also an indication of osteoporosis, regardless of bone density values.

Patients with low bone mineral density (osteopenia) should be evaluated to determine their fracture risk and assess potential underlying causes. This evaluation typically includes:

Detailed medical history to identify risk factors
Laboratory tests to rule out secondary causes of bone loss (e.g., vitamin D deficiency, hormonal imbalances)
Assessment of lifestyle factors, such as diet, physical activity, and smoking cessation
Evaluation of potential medication-related causes of bone loss
Patients undergoing treatment for osteoporosis should be monitored to assess their response to therapy and evaluate the effectiveness of the treatment. Monitoring may involve the following:
Repeat bone density testing: Periodic DXA scans are recommended to assess changes in bone mineral density over time.
Fracture evaluation: Assessing fracture incidence can help determine whether the treatment is effectively reducing the risk of fractures.
Clinical evaluation: Regular follow-up visits with the healthcare provider to assess overall health, medication adherence, and any potential side effects.

The frequency of monitoring may vary depending on the specific treatment plan and individual patient characteristics. It is essential to follow the guidance and recommendations provided by your healthcare provider to ensure proper evaluation and monitoring while undergoing osteoporosis treatment.
it is generally accepted that all women 65 and over should have a bone density test and similarly, all men 70 and over should have a baseline test. For women between 50 and 65 with risk factors such as a fragility fracture, family history of a parent who broke there hip, chronic use of prednisone, a diagnosis of rheumatoid arthritis, or current smoking, a bone density should be performed. Importantly, many patients want to know what their bone density is at that point in time to help them develop a more proactive lifestyle to prevent further bone loss

For many younger than 70 with such risk factors, the same would hold

A diagnosis of osteoporosis is established in many ways
1. If someone has a clinical hip fracture or vertebral / spine fracture, a diagnosis is established
2. If somebody has a bone density study in their T-score is -2.5 or worse and they are over 50 and or postmenopausal, diagnosis is made
3. Patients with low bone mass ( T-score of -1.1 to -2.4 ) who have a fracture of the wrist, humerus or pelvis meet a clinical diagnosis of osteoporosis
4. patients with low bone mass who have FRAX scores of 20 percent for major osteoporosis risk or 3 percent for hip fracture risk meet the diagnosis. The FRAX tool was developed by the world health organization because we realized that patients with low bone mass can fracture as well as patients who have T-scores in the osteoporosis range
5. Patients were taking chronic prednisone therapy for 3 months or longer who meet criteria developed by the American College of Rheumatology also meet a diagnosis

Patients who have low bone mass need to have a FRAX calculation. The FRAX calculation takes into account other risk factors besides bone density and they include age, sex, height and weight, current smoking status, presence of rheumatoid arthritis, whether someone sustained fracture, and whether either parent fractured there hip

Again the FRAX tool gives 2 fracture probabilities, 1 called the major osteoporosis fracture risk which includes the risk of hip, wrist, spine or humerus fractures. The other fracture probability is the hip fracture risk

The important point his low bone mass needs to be carefully evaluated and many patients with low bone mass may meet criteria for treatment

The most common method used for response to therapy is repeat bone density testing. However, other physicians will sometimes use markers of biochemical turnover which are breakdown products of collagen and proteins that correlate with active bone loss or active bone formation. Most commonly use tests are CTX and P1NP
Sounds like you are doing a school project. A bone scan is the best test.